human mertk peptide (R&D Systems)
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Structured Review
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human mertk peptide
Human Mertk Peptide, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 14 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+mertk/Human+C-Peptide+Antibody/pmc13032267-67-15-18
Average 94 stars, based on 14 article reviews
Human Mertk Peptide, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 14 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+mertk/Human+C-Peptide+Antibody/pmc13032267-67-15-18
Average 94 stars, based on 14 article reviews
human mertk peptide - by Bioz Stars,
2026-10
94/100 stars
Images
1) Product Images from "RGX-019-MMAE inhibits leukemia progression by targeting MER proto-oncogene tyrosine kinase (MERTK) in acute myeloid leukemia"
Article Title: RGX-019-MMAE inhibits leukemia progression by targeting MER proto-oncogene tyrosine kinase (MERTK) in acute myeloid leukemia
Journal: Journal of Experimental & Clinical Cancer Research : CR
doi: 10.1186/s13046-026-03657-y
Figure Legend Snippet: The antibody-drug conjugate RGX-019-MMAE induced cytotoxic activity in MERTK-expressing AML cell lines. A MERTK expression in the indicated AML cell lines; leukemic cells (1 × 10 6 ) were stained with anti-MERTK-APC antibody, and the expression was measured by flow cytometry. Data are plotted as mean values with error bars representing standard error. B - F Bar graph showing the percentage of relative luminescence in Kasumi 1 ( B ), OCI-AML3 ( C ), MOLM-13 ( D ), MOLM-14 ( E ), and MV4-11 ( F ) cells treated with the indicated concentrations of RGX-019-MMAE and monoclonal antibody RGX-019. Data are plotted as mean values with error bars representing standard error (Student unpaired t -test). * p ≤0.05, ** p ≤0.01, *** p ≤0.001, **** p ≤0.0001. UT = untreated
Techniques Used: Activity Assay, Expressing, Staining, Flow Cytometry
Figure Legend Snippet: The antibody-drug conjugate RGX-019-MMAE induced cytotoxic activity in MERTK-expressing AML primary cells. A - D Bar graphs show the percentage of relative luminescence in primary AML cells, RGX946 ( A ), RGX694 ( B ), RGX702 ( C ), and RGX470 ( D ) treated with the indicated concentrations of RGX-019-MMAE or the monoclonal antibody RGX-019. Data are plotted as mean values with error bars representing standard error (Student unpaired t -test). E Representative figures of colony-forming units for normal peripheral blood mononuclear cells in response to DMSO and indicated concentrations of RGX-019-MMAE and RGX-019. Data are plotted as mean values with error bars representing standard error (Student unpaired t -test) * p ≤0.05, ** p ≤0.01, *** p ≤0.001, **** p ≤0.0001
Techniques Used: Activity Assay, Expressing
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other:Article Title: A feeding-induced myokine modulates glucose homeostasis. Article Snippet: Maintaining blood glucose homeostasis during fasting and feeding is crucial for the prevention of dysregulation that can lead to either hypoor hyperglycaemia.. Here we identified feimin, encoded by a gene with a previously unknown function (B230219D22Rik in mice, C5orf24 in humans), as a key modulator of glucose homeostasis.. Feimin is secreted from skeletal muscle during feeding and binds to its receptor, receptor protein tyrosine kinase Mer (MERTK), promoting glucose uptake and inhibiting glucose production by activation of AKT. Article Title: Inflammatory crosstalk impairs phagocytic receptors and aggravates atherosclerosis in clonal hematopoiesis in mice Article Snippet: Then the 549 membranes were blocked with 5% non-fat milk in TBST and immunostained with primary 550 antibodies, anti-p-Syk (cell signaling technology 2710s, 1:1000), anti-Syk (cell signaling 551 technology 13198, 1:1000), anti-p-AKT (cell signaling technology 4060s, 1:1000) anti-552 AKT (cell signaling technology 4685, 1:1000), anti-cleaved Gasdermin D (cell signaling 553 technology 10137S, 1:1000), anti-p-β-Catenin (cell signaling technology 5651, 1:1000), 554 anti-β-Catenin (cell signaling technology 8480S, 1:1000), anti-PDGFB (abcam 555 ab23914,1:1000), anti-Histone H3 (cell signaling technology 4499, 1:1000), anti-MERTK 556 27 ( Article Title: Inflammatory crosstalk impairs phagocytic receptors and aggravates atherosclerosis in clonal hematopoiesis in mice Article Snippet: Then, the membranes were blocked with 5% nonfat milk in TBST and immunostained with the primary antibodies anti–p-Syk (Cell Signaling Technology, 2710s, 1:1,000), anti-Syk (Cell Signaling Technology, 13198, 1:1,000), anti–p-AKT (Cell Signaling Technology, 4060s, 1:1,000), anti-AKT (Cell Signaling Technology, 4685, 1:1,000), anti–cleaved gasdermin D (Cell Signaling Technology, 10137S, 1:1,000), anti–p–β-catenin (Cell Signaling Technology, 5651, 1:1,000), anti–β-catenin (Cell Signaling Technology, 8480S, 1:1,000), anti-PDGFB (Abcam, ab23914,1:1,000), anti–histone H3 (Cell Signaling Technology, 4499, 1:1,000), Bioprocessing:Article Title: Cardiac Macrophages Promote Polarization of Macrophages toward M2 Phenotype to Improve Myocardial Remodeling via NGAL after Myocardial Infarction. Article Snippet: Several studies have shown that the number of circulating neutrophils or the levels of their secreted factors, including Neutrophil Gelatinase-Associated Lipocalin (NGAL), in plasma are associated with the prognosis and mortality of patients with myocardial infarction (MI).. However, the underlying mechanisms remain unclear.. MI was induced in mice by permanent ligation of the left anterior descending coronary artery. Immunoprecipitation:Article Title: Exploiting structural variability in the kinase back-pocket to modulate polypharmacology of TAM inhibitors. Article Snippet: TAM kinases play dual roles in tumor cells and the innate immune system.. While they have redundant functions, the TAM kinases are differentially required in specific contexts.. Therefore, inhibition of specific TAM kinases or pairs of TAM kinases will be desirable in different tumor types. Article Title: Discovery of Novel TYRO3/MERTK Dual Inhibitors. 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